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Publicaciones de últimos 5 años


Fernández A., M. González, I. Malbrán, R.F. Vázquez, S.M. Maté, F. Guzmán, L.S. Bakás & S. Vairo Cavalli (2022) “Histidine 19 Residue Is Essential for Cell Internalization of Antifungal Peptide SmAPα1-21 Derived from the α-Core of the Silybum marianum Defensin DefSm2-D in Fusarium graminearum“. Antibiotics, 11(11), 1501.

Hermet M., R. Yanis Espinosa, M.E. Fait, M.Y. de las Zulueta Díaz, S. Morcelle, L.S. Bakás, H.A. Alvarez & M.L. Fanani (2022) “Arginine-based surfactants alter the rheological and in-plane structural properties of stratum corneum model membranes”. Journal of Colloid and Interface Science.

Besada L.N., M. Hermet, L. Bakas, A.M. Cortizo & M.S. Cortizo (2022) “Polymersomes as nanocarriers of vitamin D3: morphological and in vitro characterization”. J Nanopart Res 24, 180.

Salese L., C.S. Liggieri, D.L. Bernik & M.A. Bruno (2022) “Characterization of the fruit proteolytic system of Bromelia serra Griseb. (Bromeliaceae) and its application in bioactive peptides release”. Journal of Food Biochemistry, 46(1), 1–13.

Gómez Herrera M.D., P. Alayón Luaces, C. Liggieri, M. Bruno & M.V. Avanza (2022) “Proteolytic characterization of a novel enzymatic extract from Bromelia serra leaves”. Anais da Academia Brasileira de Ciências, 94 (4), e20201871. ISSN 1678-2690.

Ozón B., J. Cotabarren, T. Valicenti, M.G. Parisi & W.D. Obregón (2022). “Chia expeller: A promising source of antioxidant, antihypertensive and antithrombotic peptides produced by enzymatic hydrolysis with Alcalase and Flavourzyme”. Food chemistry, 380 (December 2021), 132185.

Rocha G.F., J. Cotabarren, W.D. Obregón, G. Fernández, A.M. Rosso & M.G. Parisi (2021). “Milk-clotting and hydrolytic activities of an aspartic protease from Salpichroa origanifolia fruits on individual caseins”. International Journal of Biological Macromolecules, 192 (September), 931–938.


Toledo M.V., C. José, C.R. Llerena Suster, S.E. Collins, R. Portela, M.A. Bañares & L.E. Briand (2021). “Catalytic and molecular insights of the esterification of ibuprofen and ketoprofen with glycerol”. Molecular Catalysis, 513, 111811.

Cotabarren J., B. Ozón, S. Claver, J. Garcia-Pardo & W.D. Obregón (2021) “Purification and Identification of Novel Antioxidant Peptides Isolated from Geoffroea decorticans Seeds with Anticoagulant Activity”. Pharmaceutics, 13(8):1153.

López-Rodríguez A., J. Mayorga, D. Flaiga, G. Fuentes, J. Cotabarren, W.D. Obregón & P.I. Gómez (2021) “Comparison of two strains of the edible cyanobacteria Arthrospira: Biochemical characterization and antioxidant properties”. Food Bioscience. 42:101144.

Cotabarren J., Claver S., Payrol J.A., Garcia-Pardo J. & Obregón W.D. (2021) “Purification and characterization of a novel thermostable papain inhibitor from Moringa oleifera with antimicrobial
and anticoagulant properties”. Pharmaceutics, 13(4):512. pharmaceutics13040512

Fernández A., M.L. Colombo, L. Curto, G.E. Gómez, J.M. Delfino, F. Guzmán Quimbayo, L. Bakás, I. Malbrán & S. Vairo Cavalli (2021). “Peptides derived from the alpha-core and gamma-core regions of a putative Silybum marianum flower defensin show antifungal activity against Fusarium graminearum“. Frontiers in Microbiology, 17;12:632008, February.

Hermet M., M.E. Fait, R. Vazquez, S. Maté, M.A. Daza Millone, M.E. Vela, M.T. García, S.R. Morcelle & L. Bakás (2021). “Interaction of cationic surfactants with DPPC lipid membranes: effect of a novel Nα-benzoylated Arginine-based compound”. Amino acids, February.


Mateos P.S., M.B. Navas, S.R. Morcelle, C. Ruscitti, S.R. Matkovic, L.E. Briand (2020). “Insights in the biocatalyzed hydrolysis, esterification and transesterification of waste cooking oil with a vegetable lipase”. Catalysis Today, September.

Colombo M.L., C.V. Cimino, M.A. Bruno, A. Hugo, C. Liggieri, A. Fernández, S. Vairo-Cavalli (2020). “Artichoke cv. Francés flower extract as a rennet substitute: effect on textural, microstructural, microbiological, antioxidant properties, and sensory acceptance of miniature cheeses”. Journal of the Science of Food and Agriculture, August.

Reyes Jara A.M., M.A. Corrons, L. Salese, C.S. Liggieri, M.A. Bruno (2020) “Peptidases from Maclura pomifera for preparation of food protein hydrolysates: purification by single-step chromatography and characterization of Pomiferin I. Applied Biochemistry and Biotechnology.

Cotabarren J., Lufrano D., Parisi M. G., Obregón W. D. (2020) “Biotechnological and biomedical applications of plant protease inhibitors with high stability: A systematic review”. Plant Science, 292: 110398.

Cotabarren J., D.J. Broitman, E. Quiroga, W.D. Obregón (2020) “GdTI, the first thermostable trypsin inhibitor from Geoffroea decorticans seeds. A novel natural drug with potential application in biomedicine”. International Journal of Biological Macromolecules, 148: 869-879,

Cisneros S.J., J. Cotabarren, M.G. Parisi, M.W. Vasconcelos, W.D. Obregón (2020) “Purification and characterization of a novel trypsin inhibitor from Solanum tuberosum subsp. andigenum var. overa: Study of the expression levels and preliminary evaluation of its antimicrobial activity”. International Journal of Biological Macromolecules, 158: 1279-1287,

Origone A., S. Barberis, A. Illanes, F. Guzmán, G. Camí, C. Liggieri, R. Martínez, C. Bernal (2020) “Improvement of enzymatic performance of Asclepias curassavica L. proteases by immobilization. Application to the synthesis of an antihypertensive peptide”. Process Biochemistry, 95: 36-46.


Toledo M.V., C.R. Llerena Suster, C. Ruscitti, S.E. Collins, L.E. Briand (2019) “Influence of water on enzymatic esterification of racemic ketoprofen with ethanol in a solvent-free system”. Topics in catalysis. 62: 968–976.

Llerena Suster C.R., M.E. Diaz Merino, S.R. Morcelle del Valle, L.E. Briand (2019) “Lipasa B de Candida antarctica inmovilizada sobre SiO2 nanoestructurado aplicada en la esterificación enantioselectiva de ibuprofeno”. Journal of the argentinian chemical society. 106: 16-28.

Hermet M., L. Bakás, S.R. Morcelle, D.L. Bernik (2019) “Bromide counterion as a spectroscopic sensor at the interface of cetyltrimethylammonium micelles”. Spectrochimica Acta. Part A, Molecular And Biomolecular Spectroscopy. Vol. 223,

Cotabarren J., A. Rosso, M. Tellechea, J. García-Pardo, J. Lorenzo, W.D. Obregón, M.G. Parisi (2019) “Adding value to the chia (Salvia hispanica L.) expeller: Production of bioactive peptides with antioxidant properties by enzymatic hydrolysis with Papain”. Food Chemistry.

Fait M.E., L. Bakas, G.L. Garrote, S.R. Morcelle, M.C.N. Saparrat (2019) “Cationic surfactants as antifungal agents”. Applied Microbiology and Biotechnology, 103 (1): 97-112.

Fait M.E., H.P.S. da Costa, C.D.T. Freitas, L. Bakas, S.R. Morcelle (2019) Antifungal Activity of Arginine-Based Surfactants. Current Bioactive Compounds, 15: 351–359.

Sánchez D, Morcelle S, Fait M, Tonetto G, Ferreira M (2019) “Application of a Multienzymatic System from Natural Latex in Key Reactions for oil-Based Biorefineries”. Fermentation, 5: 1-18.


Errasti M.E., C.L. Natalucci, N.O. Caffini, A.E. Rotelli, A. Brullo, B. Maras, S.A. Trejo and L.M.I. López (2018) “Structural properties of macrodontain I, a cysteine protease from Pseudananas macrodontes”. Applied Biochemistry and Biotechnology.

Errasti M.E., N.O. Caffini & L.M.I. López (2018) “Proteolytic extracts of three Bromeliaceae species as eco-compatible tools for leather industry” Environmental Science and Pollution Research

Cotabarren J., M.E. Tellechea, F.X. Avilés, J. Lorenzo Rivera, W.D. Obregón (2018) “Biochemical characterization of the YBPCI miniprotein, the first carboxypeptidase inhibitor isolated from Yellow Bell Pepper (Capsicum annuum L). A novel contribution to the knowledge of miniproteins stability”. Protein Expression and Purification, 144: 55-61.

Cotabarren J., M.E. Tellechea, S.M. Tanco, (…), F.X. Avilés, W.D. Obregón (2018) “Biochemical and MALDI-TOF mass spectrometric characterization of a novel native and recombinant cystine knot miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña”. International Journal of Molecular Sciences, 19(3): 678.

Fait M.E., M. Hermet, R. Vazquez, (…), S.R. Morcelle, L. Bakas (2018) “Volume expansion of erythrocytes is not the only mechanism responsible for the protection by arginine-based surfactants against hypotonic hemolysis”. Colloids and Surfaces B: Biointerfaces, 171: 134-141.

Colombo M.L., A. Fernández, C.V. Cimino, (…), P.C. Veríssimo, S. Vairo-Cavalli (2018) “Miniature cheeses made with blends of chymosin and a vegetable rennet from flowers of Silybum marianum: Enzymatic characterization of the flower-coagulant peptidase”. Food Chemistry, 266: 223-231.

Reyes Jara A.M., C.S. Liggieri, M.A. Bruno (2018) “Preparation of soy protein hydrolysates with antioxidant activity by using peptidases from latex of Maclura pomifera fruits”. Food Chemistry, 264: 326-333.

Bárcena A., M. Bruno, A. Gennaro, M.F. Rozas, M.V. Mirífico, P.A. Balatti, M.C.N. Saparrat (2018) “Melanins from two selected isolates of Pseudocercospora griseola grown in-vitro: Chemical features and redox activity”. Journal of Photochemistry and Photobiology B: Biology, 186: 207-215.

Origone A., G. Bersi, A. Illanes, (…), F. Guzmán, S. Barberis (2018) “Enzymatic and chemical synthesis of new anticoagulant peptides”. Biotechnology Progress, 34 (5): 1093-1101.