Publicaciones de últimos 5 años


Llerena Suster C.R., M.V. Toledo, S.R. Matkovic, S.R. Morcelle & L.E. Briand (2023) “Rational Design of a Biocatalyst Based on Immobilized CALB onto Nanostructured SiO2”. Catalysts, 13(3), 625.

Fait M.E., P.D. Grillo, G.L. Garrote, E.D. Prieto, R.F. Vázquez, M.C.N. Saparrat & S.R. Morcelle (2023) “Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates”. Amino Acids, 0123456789.

Cotabarren J., B.Ozón, S. Claver, F. Geier, M. Rossotti, J. Garcia-Pardo & W.D. Obregón (2023) “A multifunctional trypsin protease inhibitor from yellow bell pepper seeds: uncovering its dual antifungal and hypoglycemic properties”. Pharmaceutics, 15(3):781.

Bertucci J.I., L. Salese, C.S. Liggieri, G.L. Garrote, & M.A. Bruno (2023) “Preparation of whey protein hydrolysates with ACE‐inhibitory activity using cysteine peptidases from Bromelia hieronymi Mez.(Bromeliaceae)”. International Journal of Dairy Technology. First published: 05 March 2023.


Fernández A., M. González, I. Malbrán, R.F. Vázquez, S.M. Maté, F. Guzmán, L.S. Bakás & S. Vairo Cavalli (2022) “Histidine 19 Residue Is Essential for Cell Internalization of Antifungal Peptide SmAPα1-21 Derived from the α-Core of the Silybum marianum Defensin DefSm2-D in Fusarium graminearum“. Antibiotics, 11(11), 1501.

Hermet M., R. Yanis Espinosa, M.E. Fait, M.Y. de las Zulueta Díaz, S. Morcelle, L.S. Bakás, H.A. Alvarez & M.L. Fanani (2022) “Arginine-based surfactants alter the rheological and in-plane structural properties of stratum corneum model membranes”. Journal of Colloid and Interface Science.

Besada L.N., M. Hermet, L. Bakas, A.M. Cortizo & M.S. Cortizo (2022) “Polymersomes as nanocarriers of vitamin D3: morphological and in vitro characterization”. J Nanopart Res 24, 180.

Salese L., C.S. Liggieri, D.L. Bernik & M.A. Bruno (2022) “Characterization of the fruit proteolytic system of Bromelia serra Griseb. (Bromeliaceae) and its application in bioactive peptides release”. Journal of Food Biochemistry, 46(1), 1–13.

Gómez Herrera M.D., P. Alayón Luaces, C. Liggieri, M. Bruno & M.V. Avanza (2022) “Proteolytic characterization of a novel enzymatic extract from Bromelia serra leaves”. Anais da Academia Brasileira de Ciências, 94 (4), e20201871. ISSN 1678-2690.

Ozón B., J. Cotabarren, T. Valicenti, M.G. Parisi & W.D. Obregón (2022). “Chia expeller: A promising source of antioxidant, antihypertensive and antithrombotic peptides produced by enzymatic hydrolysis with Alcalase and Flavourzyme”. Food chemistry, 380 (December 2021), 132185.

Rocha G.F., J. Cotabarren, W.D. Obregón, G. Fernández, A.M. Rosso & M.G. Parisi (2021). “Milk-clotting and hydrolytic activities of an aspartic protease from Salpichroa origanifolia fruits on individual caseins”. International Journal of Biological Macromolecules, 192 (September), 931–938.


Toledo M.V., C. José, C.R. Llerena Suster, S.E. Collins, R. Portela, M.A. Bañares & L.E. Briand (2021). “Catalytic and molecular insights of the esterification of ibuprofen and ketoprofen with glycerol”. Molecular Catalysis, 513, 111811.

Cotabarren J., B. Ozón, S. Claver, J. Garcia-Pardo & W.D. Obregón (2021) “Purification and Identification of Novel Antioxidant Peptides Isolated from Geoffroea decorticans Seeds with Anticoagulant Activity”. Pharmaceutics, 13(8):1153.

López-Rodríguez A., J. Mayorga, D. Flaiga, G. Fuentes, J. Cotabarren, W.D. Obregón & P.I. Gómez (2021) “Comparison of two strains of the edible cyanobacteria Arthrospira: Biochemical characterization and antioxidant properties”. Food Bioscience. 42:101144.

Cotabarren J., Claver S., Payrol J.A., Garcia-Pardo J. & Obregón W.D. (2021) “Purification and characterization of a novel thermostable papain inhibitor from Moringa oleifera with antimicrobial
and anticoagulant properties”. Pharmaceutics, 13(4):512. pharmaceutics13040512

Fernández A., M.L. Colombo, L. Curto, G.E. Gómez, J.M. Delfino, F. Guzmán Quimbayo, L. Bakás, I. Malbrán & S. Vairo Cavalli (2021). “Peptides derived from the alpha-core and gamma-core regions of a putative Silybum marianum flower defensin show antifungal activity against Fusarium graminearum“. Frontiers in Microbiology, 17;12:632008, February.

Hermet M., M.E. Fait, R. Vazquez, S. Maté, M.A. Daza Millone, M.E. Vela, M.T. García, S.R. Morcelle & L. Bakás (2021). “Interaction of cationic surfactants with DPPC lipid membranes: effect of a novel Nα-benzoylated Arginine-based compound”. Amino acids, February.


Mateos P.S., M.B. Navas, S.R. Morcelle, C. Ruscitti, S.R. Matkovic, L.E. Briand (2020). “Insights in the biocatalyzed hydrolysis, esterification and transesterification of waste cooking oil with a vegetable lipase”. Catalysis Today, September.

Colombo M.L., C.V. Cimino, M.A. Bruno, A. Hugo, C. Liggieri, A. Fernández, S. Vairo-Cavalli (2020). “Artichoke cv. Francés flower extract as a rennet substitute: effect on textural, microstructural, microbiological, antioxidant properties, and sensory acceptance of miniature cheeses”. Journal of the Science of Food and Agriculture, August.

Reyes Jara A.M., M.A. Corrons, L. Salese, C.S. Liggieri, M.A. Bruno (2020) “Peptidases from Maclura pomifera for preparation of food protein hydrolysates: purification by single-step chromatography and characterization of Pomiferin I. Applied Biochemistry and Biotechnology.

Cotabarren J., Lufrano D., Parisi M. G., Obregón W. D. (2020) “Biotechnological and biomedical applications of plant protease inhibitors with high stability: A systematic review”. Plant Science, 292: 110398.

Cotabarren J., D.J. Broitman, E. Quiroga, W.D. Obregón (2020) “GdTI, the first thermostable trypsin inhibitor from Geoffroea decorticans seeds. A novel natural drug with potential application in biomedicine”. International Journal of Biological Macromolecules, 148: 869-879,

Cisneros S.J., J. Cotabarren, M.G. Parisi, M.W. Vasconcelos, W.D. Obregón (2020) “Purification and characterization of a novel trypsin inhibitor from Solanum tuberosum subsp. andigenum var. overa: Study of the expression levels and preliminary evaluation of its antimicrobial activity”. International Journal of Biological Macromolecules, 158: 1279-1287,

Origone A., S. Barberis, A. Illanes, F. Guzmán, G. Camí, C. Liggieri, R. Martínez, C. Bernal (2020) “Improvement of enzymatic performance of Asclepias curassavica L. proteases by immobilization. Application to the synthesis of an antihypertensive peptide”. Process Biochemistry, 95: 36-46.


Toledo M.V., C.R. Llerena Suster, C. Ruscitti, S.E. Collins, L.E. Briand (2019) “Influence of water on enzymatic esterification of racemic ketoprofen with ethanol in a solvent-free system”. Topics in catalysis. 62: 968–976.

Llerena Suster C.R., M.E. Diaz Merino, S.R. Morcelle del Valle, L.E. Briand (2019) “Lipasa B de Candida antarctica inmovilizada sobre SiO2 nanoestructurado aplicada en la esterificación enantioselectiva de ibuprofeno”. Journal of the argentinian chemical society. 106: 16-28.

Hermet M., L. Bakás, S.R. Morcelle, D.L. Bernik (2019) “Bromide counterion as a spectroscopic sensor at the interface of cetyltrimethylammonium micelles”. Spectrochimica Acta. Part A, Molecular And Biomolecular Spectroscopy. Vol. 223,

Cotabarren J., A. Rosso, M. Tellechea, J. García-Pardo, J. Lorenzo, W.D. Obregón, M.G. Parisi (2019) “Adding value to the chia (Salvia hispanica L.) expeller: Production of bioactive peptides with antioxidant properties by enzymatic hydrolysis with Papain”. Food Chemistry.

Fait M.E., L. Bakas, G.L. Garrote, S.R. Morcelle, M.C.N. Saparrat (2019) “Cationic surfactants as antifungal agents”. Applied Microbiology and Biotechnology, 103 (1): 97-112.

Fait M.E., H.P.S. da Costa, C.D.T. Freitas, L. Bakas, S.R. Morcelle (2019) Antifungal Activity of Arginine-Based Surfactants. Current Bioactive Compounds, 15: 351–359.

Sánchez D, Morcelle S, Fait M, Tonetto G, Ferreira M (2019) “Application of a Multienzymatic System from Natural Latex in Key Reactions for oil-Based Biorefineries”. Fermentation, 5: 1-18.